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Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

Human Male Sex: Endocrine Disruption and Male Reproductive Wellness

9.1 Introduction

Male sexuality is decided genetically during the time of fertilization by the existence of the Y chromosome within the spermatozoan since it fuses using the X-chromosome-containing ovum, additionally the region that is sex-determining of Y chromosome (SRY) then drives the bipotential gonad regarding the embryo to be a testis through hormone-independent mechanisms 1,2. Nonetheless, when the testis that is early created, growth of the total male phenotype, including further testicular development (masculinization), becomes entirely determined by a complex system of endocrine signals, especially hormones secreted from the testes 2. People who lack any gonads are phenotypically female 1 and endocrine intervention is needed to change the default feminine phenotype to be male 2. Continue reading Human Male Sex: Endocrine Disruption and Male Reproductive Wellness